z-logo
open-access-imgOpen Access
Matrix extracellular phosphoglycoprotein causes phosphaturia in rats by inhibiting tubular phosphate reabsorption
Author(s) -
Hamish Dobbie,
Robert J. Unwin,
Nuno Faria,
David G. Shirley
Publication year - 2007
Publication title -
nephrology dialysis transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.654
H-Index - 168
eISSN - 1460-2385
pISSN - 0931-0509
DOI - 10.1093/ndt/gfm535
Subject(s) - reabsorption , endocrinology , medicine , renal physiology , excretion , phosphate , extracellular fluid , renal function , fibroblast growth factor 23 , extracellular , kidney , chemistry , calcium , parathyroid hormone , biochemistry
Matrix extracellular phosphoglycoprotein (MEPE), first isolated from tumour-derived tissue from a patient with oncogenic hypophosphataemia, is a putative phosphatonin that has received much less attention than fibroblast growth factor-23. To date, its effect on renal tubular phosphate reabsorption remains undefined.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.
Having issues? You can contact us here
Accelerating Research

Address

John Eccles House
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom