High plasma phosphate as a risk factor for decline in renal function and mortality in pre-dialysis patients | Zendy

Nora Voormolen | Zendy; Marlies Noordzij | Zendy; Diana C. Grootendorst | Zendy; Ivo Beetz | Zendy; Y W J Sijpkens | Zendy; Jeannette G. van Manen | Zendy; E. W. Boeschoten | Zendy; R. M. Huisman | Zendy; Raymond T. Krediet | Zendy; Friedo W. Dekker | Zendy

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High plasma phosphate as a risk factor for decline in renal function and mortality in pre-dialysis patients

Author(s) -

Nora Voormolen,

Marlies Noordzij,

Diana C. Grootendorst,

Ivo Beetz,

Y W J Sijpkens,

Jeannette G. van Manen,

E. W. Boeschoten,

R. M. Huisman,

Raymond T. Krediet,

Friedo W. Dekker

Publication year - 2007

Publication title -

nephrology dialysis transplantation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.654

H-Index - 168

eISSN - 1460-2385

pISSN - 0931-0509

DOI - 10.1093/ndt/gfm286

Subject(s) - medicine , renal function , dialysis , kidney disease , urology , phosphate binder , phosphate , hemodialysis , risk factor , gastroenterology , renal replacement therapy , endocrinology , hyperphosphatemia , biochemistry , chemistry

Hyperphosphataemia is associated with increased mortality in patients with chronic kidney disease (CKD) stage IV or on dialysis. Furthermore, in animal studies, elevated plasma phosphate has been shown to be associated with an accelerated decline in renal function. The aim of this study was to determine the association of plasma phosphate with renal function loss and mortality in CKD stage IV-V pre-dialysis patients with GFR <20 ml/min/1.73 m(2).

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