Influence of cytokine gene polymorphisms on erythropoetin dose requirements in chronic haemodialysis patients | Zendy

Matthias Girndt | Zendy; Peter Stenvinkel | Zendy; Christof Ulrich | Zendy; John Axelsson | Zendy; Louise Nordfors | Zendy; Peter Bárány | Zendy; Juan Jesús Carrero | Zendy; Gunnar H. Heine | Zendy; Harald Kaul | Zendy; Hans Köhler | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Influence of cytokine gene polymorphisms on erythropoetin dose requirements in chronic haemodialysis patients

Author(s) -

Matthias Girndt,

Peter Stenvinkel,

Christof Ulrich,

John Axelsson,

Louise Nordfors,

Peter Bárány,

Juan Jesús Carrero,

Gunnar H. Heine,

Harald Kaul,

Hans Köhler

Publication year - 2007

Publication title -

nephrology dialysis transplantation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.654

H-Index - 168

eISSN - 1460-2385

pISSN - 0931-0509

DOI - 10.1093/ndt/gfm244

Subject(s) - medicine , cytokine , kidney disease , immunology , creatinine , allele , interleukin 6 , genotype , inflammation , gene , biology , genetics

Chronic inflammation influences renal anaemia and reduce erythropoetin effectiveness. Chronic kidney disease and haemodialysis (HD) induce elevated cytokine and C-reactive protein (CRP) levels at an inter-individually variable extent. These differences are in part due to polymorphisms within cytokine genes, e.g. for pro-inflammatory interleukin-6 (IL-6) and anti-inflammatory interleukin-10 (IL-10). We hypothesized that these polymorphisms influence erythropoetin effectiveness.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research