The AN69 ST haemodialysis membrane under conditions of two different extracorporeal circuit rinse protocols a comparison of thrombogenicity parameters | Zendy

Pavlína Richtrová | Zendy; K Opatrný | Zendy; Ladislav Vít | Zendy; F Sefrna | Zendy; R. Perlik | Zendy

Open Access

The AN69 ST haemodialysis membrane under conditions of two different extracorporeal circuit rinse protocols a comparison of thrombogenicity parameters

Author(s) -

Pavlína Richtrová,

K Opatrný,

Ladislav Vít,

F Sefrna,

R. Perlik

Publication year - 2007

Publication title -

nephrology dialysis transplantation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.654

H-Index - 168

eISSN - 1460-2385

pISSN - 0931-0509

DOI - 10.1093/ndt/gfm137

Subject(s) - thrombogenicity , heparin , medicine , platelet , platelet factor 4 , saline , urology , membrane , platelet activation , pharmacology , chromatography , chemistry , biochemistry

Thrombogenicity is an important parameter of haemodialysis (HD) membrane biocompatibility. The surface of the polyacrylonitrile AN69 ST membrane is coated with a polyethylenimine. This modification allows heparin adsorption. The binding of heparin to the membrane surface occurs during priming of the extracorporeal circuit (ECC) by rinsing it with saline and heparin. Our aims were to assess and compare the thrombogenicity of the AN69 ST membrane under conditions of two extracorporeal circuit (ECC) rinse protocols-with and without unfractionated heparin (UFH).

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