Open AccessExpression of filtrin in human glomerular diseases
Author(s) -
Pekka Ihalmo,
Holger Schmid,
Maria Pia Rastaldi,
Deborah Mattinzoli,
Robyn G. Langham,
Pauliina Luimula,
Riika Kilpikari,
Markus Lassila,
R. E. Gilbert,
Dontscho Kerjaschki,
Matthias Kretzler,
H. Holthofer
Publication year - 2007
Publication title -
nephrology dialysis transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.654
H-Index - 168
eISSN - 1460-2385
pISSN - 0931-0509
DOI - 10.1093/ndt/gfm135
Subject(s) - nephrin , podocin , podocyte , slit diaphragm , medicine , focal segmental glomerulosclerosis , pathology , proteinuria , housekeeping gene , glomerulosclerosis , gene expression , kidney , biology , gene , genetics
Filtrin (NEPH3/KIRREL2) is a recently characterized member of the nephrin-like proteins of the immunoglobulin superfamily, and it has been suggested to participate in the maintenance of the glomerular filtration barrier in the kidney. In this study, the gene and protein expression of filtrin were examined in patients with acquired proteinuric diseases.
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