The effect of pH-neutral peritoneal dialysis fluids on adipokine secretion from cultured adipocytes | Zendy

Daniel Teta | Zendy; Marc Maillard | Zendy; Andrée Tedjani | Zendy; Jutta PasslickDeetjen | Zendy; Michel Burnier | Zendy

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The effect of pH-neutral peritoneal dialysis fluids on adipokine secretion from cultured adipocytes

Author(s) -

Daniel Teta,

Marc Maillard,

Andrée Tedjani,

Jutta PasslickDeetjen,

Michel Burnier

Publication year - 2006

Publication title -

nephrology dialysis transplantation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.654

H-Index - 168

eISSN - 1460-2385

pISSN - 0931-0509

DOI - 10.1093/ndt/gfl698

Subject(s) - adipokine , medicine , peritoneal dialysis , secretion , endocrinology , adipocyte , adipose tissue , leptin , obesity

Adipokines are a group of fat-secreted hormones and cytokines, including leptin and adiponectin, with important functions in humans. Peritoneal dialysis (PD) is associated with markedly raised plasma adipokines, suggesting increased production in this setting. We have shown that low pH down-regulates leptin production. The current study was designed to test if novel pH-neutral PD fluids may regulate leptin and adiponectin secretion in vitro.

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