Genome scan of glomerular filtration rate and albuminuria: the HyperGEN study
Author(s) -
José Manuel León Jurado,
B. I. Freedman,
Michael B. Miller,
K. E. North,
S C Hunt,
J H Eckfeldt,
Cora E. Lewis,
Aldi T. Kraja,
Luc Djoussé,
D.K. Arnett
Publication year - 2006
Publication title -
nephrology dialysis transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.654
H-Index - 168
eISSN - 1460-2385
pISSN - 0931-0509
DOI - 10.1093/ndt/gfl674
Subject(s) - albuminuria , renal function , medicine , diabetes mellitus , kidney disease , creatinine , genetic linkage , locus (genetics) , linkage (software) , urology , endocrinology , genetics , biology , gene
Albuminuria and reduced glomerular filtration rate (GFR) are markers of renal dysfunction associated with hypertension. We performed genome-wide scans to detect loci impacting these parameters in 1251 African American (AAs) and 1129 European American (EAs) hypertensive siblings from the Hypertension Genetic Epidemiology Network study.
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