Influence of haemodialysis and left ventricular failure on peripheral A2A adenosine receptor expression | Zendy

Louis Carrega | Zendy; Emmanuel Fenouillet | Zendy; Philippe Giaime | Zendy; A. Charavil | Zendy; Laurence Mercier | Zendy; V. Gérolami | Zendy; J.-L. Bergé-Lefranc | Zendy; Yvon Berland | Zendy; Jean Ruf | Zendy; A Saadjian | Zendy; Bertrand Dussol | Zendy; Régis Guieu | Zendy

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Influence of haemodialysis and left ventricular failure on peripheral A2A adenosine receptor expression

Author(s) -

Louis Carrega,

Emmanuel Fenouillet,

Philippe Giaime,

A. Charavil,

Laurence Mercier,

V. Gérolami,

J.-L. Bergé-Lefranc,

Yvon Berland,

Jean Ruf,

A Saadjian,

Bertrand Dussol,

Régis Guieu

Publication year - 2006

Publication title -

nephrology dialysis transplantation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.654

H-Index - 168

eISSN - 1460-2385

pISSN - 0931-0509

DOI - 10.1093/ndt/gfl665

Subject(s) - medicine , cardiology , adenosine , peripheral , hemodialysis , heart failure

Haemodialysis (HD) sometimes accelerates left ventricular failure (LVF). As adenosine (ADO) is strongly implicated in cardiovascular functions, particularly via A(2A) receptor activation and as changes of peripheral A(2A) receptors mirror changes occurring in the cardiovascular system, we examined the influence of HD and LVF on both ADO plasma concentration and the expression of A(2A) receptors (i.e. Bmax, K(D) and mRNA amount) of peripheral blood mononuclear cells.

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