Effective control of persistent hyperparathyroidism with cinacalcet in renal allograft recipients | Zendy

Andreas L. Serra | Zendy; Reto Savoca | Zendy; Andreas Huber | Zendy; Urs Hepp | Zendy; A. Delsignore | Zendy; Martin Hersberger | Zendy; Rudolf P. Wüthrich | Zendy

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Effective control of persistent hyperparathyroidism with cinacalcet in renal allograft recipients

Author(s) -

Andreas L. Serra,

Reto Savoca,

Andreas Huber,

Urs Hepp,

A. Delsignore,

Martin Hersberger,

Rudolf P. Wüthrich

Publication year - 2006

Publication title -

nephrology dialysis transplantation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.654

H-Index - 168

eISSN - 1460-2385

pISSN - 0931-0509

DOI - 10.1093/ndt/gfl560

Subject(s) - cinacalcet , medicine , hypercalcaemia , endocrinology , hyperparathyroidism , urology , secondary hyperparathyroidism , parathyroid hormone , creatinine , calcium

Cinacalcet rapidly normalizes serum calcium and reduces intact parathyroid hormone (PTH) levels in renal transplant patients with hypercalcaemia and persistent hyperparathyroidism. The aim of this study is to evaluate the 6 months efficacy of cinacalcet and the effect of cinacalcet withdrawal on serum calcium and PTH in such patients. Furthermore, the impact of cinacalcet on bone turnover and quality of life was assessed.

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