Open AccessFunctional impairment of monocyte-derived dendritic cells in patients with severe chronic kidney disease
Author(s) -
Martijn A. Verkade,
Corné J. van Druningen,
L. M. B. Vaessen,
Dennis A. Hesselink,
Willem Weimar,
Michiel G.H. Betjes
Publication year - 2006
Publication title -
nephrology dialysis transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.654
H-Index - 168
eISSN - 1460-2385
pISSN - 0931-0509
DOI - 10.1093/ndt/gfl519
Subject(s) - medicine , kidney disease , monocyte , functional impairment , disease , immunology
Dendritic cells (DCs) are antigen-presenting cells that are pivotal for the initiation of the primary immune response. Patients with chronic kidney disease (CKD) with or without chronic intermittent haemodialysis (CIHD) show an impaired immune response. Dysfunction of DCs may underlie this phenomenon.
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