Urinary tumour necrosis factor- excretion independently correlates with clinical markers of glomerular and tubulointerstitial injury in type 2 diabetic patients | Zendy

Juan F. NavarroGonzález | Zendy; Carmen Mora | Zendy; Mercedes Muros | Zendy; J. García | Zendy

Open Access

Urinary tumour necrosis factor- excretion independently correlates with clinical markers of glomerular and tubulointerstitial injury in type 2 diabetic patients

Author(s) -

Juan F. NavarroGonzález,

Carmen Mora,

Mercedes Muros,

J. García

Publication year - 2006

Publication title -

nephrology dialysis transplantation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.654

H-Index - 168

eISSN - 1460-2385

pISSN - 0931-0509

DOI - 10.1093/ndt/gfl469

Subject(s) - medicine , diabetic nephropathy , urinary system , diabetes mellitus , urine , endocrinology , tumor necrosis factor alpha , c reactive protein , excretion , type 2 diabetes , nephropathy , gastroenterology , inflammation

Inflammation is a potential factor in the development and progression of diabetic nephropathy. The aim of this study was to analyse the relationship between the pro-inflammatory cytokine tumour necrosis factor-alpha (TNFalpha) and clinical markers of glomerular and tubulointerstitial damage [urinary albumin excretion (UAE) and urinary N-acetyl-beta-glucosaminidase (UNAG), respectively] in a large group of type 2 diabetic patients.

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