High prevalence of anti-C1q antibodies in biopsy-proven active lupus nephritis | Zendy

Marten Trendelenburg | Zendy; Margarita LópezTrascasa | Zendy; Eliška Potluková | Zendy; Solange Moll | Zendy; Stephan Regenass | Zendy; Véronique FrémeauxBacchi | Zendy; Jorge Martínez-Ara | Zendy; Eva Jančová | Zendy; María L. Picazo | Zendy; Eva Honsová | Zendy; Vladimı́r Tesař | Zendy; Salima Sadallah | Zendy; Jürg A. Schifferli | Zendy

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High prevalence of anti-C1q antibodies in biopsy-proven active lupus nephritis

Author(s) -

Marten Trendelenburg,

Margarita LópezTrascasa,

Eliška Potluková,

Solange Moll,

Stephan Regenass,

Véronique FrémeauxBacchi,

Jorge Martínez-Ara,

Eva Jančová,

María L. Picazo,

Eva Honsová,

Vladimı́r Tesař,

Salima Sadallah,

Jürg A. Schifferli

Publication year - 2006

Publication title -

nephrology dialysis transplantation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.654

H-Index - 168

eISSN - 1460-2385

pISSN - 0931-0509

DOI - 10.1093/ndt/gfl436

Subject(s) - medicine , lupus nephritis , systemic lupus erythematosus , anti dsdna antibodies , dermatology , antibody , biopsy , immunology , nephritis , lupus erythematosus , disease

Anti-C1q antibodies (anti-C1q) have been shown to correlate positively with systemic lupus erythematosus (SLE) nephritis. Several clinical studies indicated a high negative predictive value, suggesting that active lupus nephritis is rarely seen in patients with no anti-C1q. However, the true prevalence of anti-C1q at the time of active lupus nephritis has not been well established. The aim of this study was to determine prospectively the prevalence of anti-C1q in proven active lupus nephritis at the time of the renal biopsy.

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