Cellular basis of diabetic nephropathy: IV Antioxidant enzyme mRNA expression levels in skin fibroblasts of type 1 diabetic sibling pairs | Zendy

M. L. Caramori | Zendy; Y. Kim | Zendy; Paola Fioretto | Zendy; Chengdong Huang | Zendy; Stephen S. Rich | Zendy; Michael E. Miller | Zendy; Greg Russell | Zendy; Michael Mauer | Zendy

Open Access

Cellular basis of diabetic nephropathy: IV Antioxidant enzyme mRNA expression levels in skin fibroblasts of type 1 diabetic sibling pairs

Author(s) -

M. L. Caramori,

Y. Kim,

Paola Fioretto,

Chengdong Huang,

Stephen S. Rich,

Michael E. Miller,

Greg Russell,

Michael Mauer

Publication year - 2006

Publication title -

nephrology dialysis transplantation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.654

H-Index - 168

eISSN - 1460-2385

pISSN - 0931-0509

DOI - 10.1093/ndt/gfl434

Subject(s) - medicine , diabetic nephropathy , sibling , diabetes mellitus , nephropathy , endocrinology , type 1 diabetes , enzyme , antioxidant , messenger rna , biochemistry , gene , biology , psychology , developmental psychology

Blunted cultured skin fibroblast (SF) antioxidant enzyme responses to hyperglycaemia are associated with diabetic nephropathy risk. The present study explores whether this association is, at least in part, genetically determined.

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