Expression and regulation of Toll-like receptors in lupus-like immune complex glomerulonephritis of MRL-Fas(lpr) mice | Zendy

Prashant S. Patole | Zendy; Rahul D. Pawar | Zendy; Maciej Lech | Zendy; Daniel Zecher | Zendy; Hanna Schmidt | Zendy; Stephan Segerer | Zendy; Andreas Ellwart | Zendy; Anna Henger | Zendy; Matthias Kretzler | Zendy; HansJoachim Anders | Zendy

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Expression and regulation of Toll-like receptors in lupus-like immune complex glomerulonephritis of MRL-Fas(lpr) mice

Author(s) -

Prashant S. Patole,

Rahul D. Pawar,

Maciej Lech,

Daniel Zecher,

Hanna Schmidt,

Stephan Segerer,

Andreas Ellwart,

Anna Henger,

Matthias Kretzler,

HansJoachim Anders

Publication year - 2006

Publication title -

nephrology dialysis transplantation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.654

H-Index - 168

eISSN - 1460-2385

pISSN - 0931-0509

DOI - 10.1093/ndt/gfl336

Subject(s) - tlr2 , lupus nephritis , tlr9 , tlr3 , glomerulonephritis , tlr7 , toll like receptor , immune system , tlr5 , immunology , innate immune system , medicine , biology , receptor , systemic lupus erythematosus , kidney , endocrinology , gene expression , disease , biochemistry , dna methylation , gene

How microbial infections exacerbate immune complex glomerulonephritis remains speculative. Toll-like receptors (TLRs) may be involved in this phenomenon, because TLRs have potent immunostimulatory functions when exposed to selected pathogen-associated molecules.

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