Open AccessTargeting of interstitial cells using a simple gene-transfer strategy
Author(s) -
Naohiko Fujii,
Yoshitaka Isaka,
Yoshitsugu Takabatake,
Masayuki Mizui,
Chigure Suzuki,
Shiro Takahara,
Takahito Ito,
Enyu Imai
Publication year - 2006
Publication title -
nephrology dialysis transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.654
H-Index - 168
eISSN - 1460-2385
pISSN - 0931-0509
DOI - 10.1093/ndt/gfl327
Subject(s) - medicine , gene transfer , electroporation , gene , fibrosis , cancer research , interstitial space , pathology , microbiology and biotechnology , genetics , biology
Interstitial fibroblasts are central to the inflammatory response during the progression of tubulointerstitial fibrosis. We examined the efficiency of a new gene transfer method that targets interstitial cells by using parenchymal injection of DNA followed by electroporation.
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