The effect of statins on urinary albumin excretion and glomerular filtration rate: results from both a randomized clinical trial and an observational cohort study | Zendy

Jarir At Thobari | Zendy; Auke H. Brantsma | Zendy; R. T. Gansevoort | Zendy; Sipke T. Visser | Zendy; Folkert W. Asselbergs | Zendy; Wiek H. van Gilst | Zendy; Paul E. de Jong | Zendy; L T W de Jong-van den Berg | Zendy

Open Access

The effect of statins on urinary albumin excretion and glomerular filtration rate: results from both a randomized clinical trial and an observational cohort study

Author(s) -

Jarir At Thobari,

Auke H. Brantsma,

R. T. Gansevoort,

Sipke T. Visser,

Folkert W. Asselbergs,

Wiek H. van Gilst,

Paul E. de Jong,

L T W de Jong-van den Berg

Publication year - 2006

Publication title -

nephrology dialysis transplantation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.654

H-Index - 168

eISSN - 1460-2385

pISSN - 0931-0509

DOI - 10.1093/ndt/gfl244

Subject(s) - medicine , fosinopril , renal function , pravastatin , randomized controlled trial , cohort , kidney disease , cohort study , urology , cholesterol , blood pressure , angiotensin converting enzyme

Statins improve cardiovascular outcome, but less is known on the renal outcome. We, therefore, studied the relationship between the use of statins and urinary albumin excretion (UAE) and glomerular filtration rate (GFR) in two settings: a randomized controlled trial (RCT) and an observational cohort study, in which patients were included to study the impact of an elevated UAE on renal and cardiovascular prognosis.

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