Positive effect of dietary soy in ESRD patients with systemic inflammation—correlation between blood levels of the soy isoflavones and the acute-phase reactants
Author(s) -
Paolo Fanti,
Reto Asmis,
Tammy Stephenson,
B. Peter Sawaya,
Adrian A. Franke
Publication year - 2006
Publication title -
nephrology dialysis transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.654
H-Index - 168
eISSN - 1460-2385
pISSN - 0931-0509
DOI - 10.1093/ndt/gfl169
Subject(s) - medicine , isoflavones , genistein , soy protein , systemic inflammation , hemodialysis , c reactive protein , inflammation , gastroenterology , kidney disease , soy isoflavones , endocrinology , pathology
Inflammation is commonly associated with malnutrition and cardiovascular disease in end-stage renal failure patients. Anti-inflammatory properties of the isoflavones, a micronutrient component of soy, have been reported in several experimental models and disease conditions, but never in renal failure. We hypothesized that dietary soy isoflavones correct laboratory evidence of systemic inflammation in haemodialysis (HD) patients with underlying high blood levels of C-reactive protein (CRP).
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