A randomized trial of saline hydration to prevent contrast nephropathy in chronic renal failure patients
Author(s) -
Bertrand Dussol,
Sophie Morange,
Anderson Loundoun,
P. Auquier,
Yvon Berland
Publication year - 2006
Publication title -
nephrology dialysis transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.654
H-Index - 168
eISSN - 1460-2385
pISSN - 0931-0509
DOI - 10.1093/ndt/gfl133
Subject(s) - medicine , furosemide , saline , theophylline , renal function , creatinine , urology , nephropathy , hypertonic saline , anesthesia , surgery , endocrinology , diabetes mellitus
Contrast nephropathy (CN) is a common cause of renal dysfunction that may be prevented by saline hydration and by drugs such as theophylline or furosemide. Whether oral saline hydration is as efficient as intravenous saline hydration is unknown. The preventive efficacy of theophylline and furosemide for CN remains controversial. The purpose of the current study was to evaluate the efficacy of oral saline hydration and of intravenous saline hydration plus theophylline or furosemide for the prevention of CN.
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