Factors increasing the risk for stone formation in adult patients with cystic fibrosis | Zendy

Maurizio Terribile | Zendy; Maria Capuano | Zendy; Giovanni Cangiano | Zendy; Vincenzo Carnovale | Zendy; Pietro Ferrara | Zendy; Michele Petrarulo | Zendy; Martino Marangella | Zendy

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Factors increasing the risk for stone formation in adult patients with cystic fibrosis

Author(s) -

Maurizio Terribile,

Maria Capuano,

Giovanni Cangiano,

Vincenzo Carnovale,

Pietro Ferrara,

Michele Petrarulo,

Martino Marangella

Publication year - 2006

Publication title -

nephrology dialysis transplantation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.654

H-Index - 168

eISSN - 1460-2385

pISSN - 0931-0509

DOI - 10.1093/ndt/gfl067

Subject(s) - medicine , urine , uric acid , hypercalciuria , hyperuricosuria , kidney stones , creatinine , cystic fibrosis , endocrinology , calcium oxalate , oxalate , kidney , kidney disease , gastroenterology , chemistry , organic chemistry

Patients with cystic fibrosis (CF) are at high risk of nephrolithiasis (NL), but controversy still exists in terms of causes, including low urine output, hypercalciuria, hyperoxaluria, hyperuricosuria and hypocitraturia. Moreover, heterozygotes (H-CF), which may exhibit altered renal concentrating and diluting ability, have never studied so far. We, therefore, evaluated the metabolic and physicochemical data of adult CF and H-CF patients, comparing them to controls (C).

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