Patients receiving maintenance dialysis have more severe functionally significant skeletal muscle wasting than patients with dialysis-independent chronic kidney disease
Author(s) -
Christopher W. McIntyre,
Nicholas M. Selby,
Mhairi K. Sigrist,
Lyndsay Pearce,
Thomas H. Mercer,
P. Naish
Publication year - 2006
Publication title -
nephrology dialysis transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.654
H-Index - 168
eISSN - 1460-2385
pISSN - 0931-0509
DOI - 10.1093/ndt/gfl064
Subject(s) - medicine , wasting , kidney disease , peritoneal dialysis , dialysis , renal function , diabetes mellitus , renal replacement therapy , cohort , skeletal muscle , hemodialysis , urology , gastroenterology , endocrinology
Chronic renal replacement therapy patients exhibit reduction in skeletal muscle function as a result of a combination of metabolic effects and muscle fibre size reduction. The aim of this study was to compare muscle mass with function in patients with chronic kidney disease (CKD) at stages 4 and 5 on haemodialysis (HD) and peritoneal dialysis (PD), and investigate the associations of muscle wasting in a cross-sectional cohort.
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