Open AccessN-acetylcysteine attenuates kidney injury in rats subjected to renal ischaemia-reperfusion
Author(s) -
Nicoletta Nitescu,
SvenErik Ricksten,
Niels Marcussen,
Börje Haraldsson,
Ulf Nilsson,
Samar Basu,
Gregor Guron
Publication year - 2006
Publication title -
nephrology dialysis transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.654
H-Index - 168
eISSN - 1460-2385
pISSN - 0931-0509
DOI - 10.1093/ndt/gfk032
Subject(s) - acetylcysteine , medicine , oxidative stress , renal function , kidney , ischemia , kidney disease , reperfusion injury , pharmacology , urology , antioxidant , biochemistry , chemistry
The aim of the present study is to examine the effects of N-acetylcysteine (NAC), a thiol-containing anti-oxidant, on renal function and morphology, and biomarkers of oxidative stress, in rats subjected to renal ischaemia-reperfusion (IR).
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