Tacrolimus combined with mycophenolate mofetil can effectively reverse C4d-positive steroid-resistant acute rejection in Chinese renal allograft recipients | Zendy

Qiquan Sun | Zendy; Zhihong Liu | Zendy; Guang Yin | Zendy; Huiping Chen | Zendy; Jinsong Chen | Zendy; Shuming Ji | Zendy; LI Leishi | Zendy

Open Access

Tacrolimus combined with mycophenolate mofetil can effectively reverse C4d-positive steroid-resistant acute rejection in Chinese renal allograft recipients

Author(s) -

Qiquan Sun,

Zhihong Liu,

Guang Yin,

Huiping Chen,

Jinsong Chen,

Shuming Ji,

LI Leishi

Publication year - 2006

Publication title -

nephrology dialysis transplantation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.654

H-Index - 168

eISSN - 1460-2385

pISSN - 0931-0509

DOI - 10.1093/ndt/gfk027

Subject(s) - mycophenolate , medicine , plasmapheresis , tacrolimus , immunoadsorption , urology , transplantation , mycophenolic acid , immunology , antibody

Tacrolimus (TAC) combined with mycophenolate mofetil (MMF) has been suggested to play a critical role in the reversal of C4d-positive acute humoral rejection (AHR) in renal transplantation, but the efficacy of using only TAC-MMF without immunoadsorption or plasmapheresis has not been investigated. On the other hand, Chinese recipients of renal grafts usually need lower doses of immunosuppressants, and their optimal treatment for acute humoral rejection has not been established.

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