The effects of highly active antiretroviral therapy on albuminuria in HIV-infected persons: results from a randomized trial | Zendy

Samir K. Gupta | Zendy; Robert A. Parker | Zendy; Gregory K. Robbins | Zendy; Michael P. Dubé | Zendy

Open Access

The effects of highly active antiretroviral therapy on albuminuria in HIV-infected persons: results from a randomized trial

Author(s) -

Samir K. Gupta,

Robert A. Parker,

Gregory K. Robbins,

Michael P. Dubé

Publication year - 2005

Publication title -

nephrology dialysis transplantation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.654

H-Index - 168

eISSN - 1460-2385

pISSN - 0931-0509

DOI - 10.1093/ndt/gfi053

Subject(s) - medicine , albuminuria , randomized controlled trial , human immunodeficiency virus (hiv) , antiretroviral therapy , kidney disease , immunology , immunopathology , viral load

Human immunodeficiency virus (HIV)-infected patients receiving highly active antiretroviral therapy (HAART) regimens, especially those containing protease inhibitors (PIs), are at increased risk for cardiovascular events. Albuminuria is a known independent predictor for the development of cardiovascular disease and may potentially increase in patients receiving PIs. Alternatively, albuminuria may improve with HAART as a result of treating renal parenchymal HIV infection. Longitudinal studies have not been performed previously addressing the effects of HAART on albuminuria.

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