Early renal failure after domino hepatic transplantation using the liver from a compound heterozygous patient with primary hyperoxaluria | Zendy

Stefan Farese | Zendy; Nicolas Trost | Zendy; Daniel Candinas | Zendy; Uyen HuynhDo | Zendy

Open Access

Early renal failure after domino hepatic transplantation using the liver from a compound heterozygous patient with primary hyperoxaluria

Author(s) -

Stefan Farese,

Nicolas Trost,

Daniel Candinas,

Uyen HuynhDo

Publication year - 2005

Publication title -

nephrology dialysis transplantation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.654

H-Index - 168

eISSN - 1460-2385

pISSN - 0931-0509

DOI - 10.1093/ndt/gfi019

Subject(s) - medicine , primary hyperoxaluria , liver transplantation , transplantation , kidney , calcineurin , economic shortage , cadaveric spasm , domino , kidney transplantation , urology , surgery , gastroenterology , linguistics , philosophy , biochemistry , chemistry , government (linguistics) , catalysis

To cover the shortage of cadaveric organs, new approaches to expand the donor pool are needed. Here we report on a case of domino liver transplantation (DLT) using an organ harvested from a compound heterozygous patient with primary hyperoxaluria (PHO), who underwent combined liver and kidney transplantation. The DLT recipient developed early renal failure with oxaluria. The time to the progression to oxalosis with renal failure in such situations is unknown, but, based on animal data, we hypothesize that calcineurin inhibitors may play a detrimental role.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research