Impact of parathyroidectomy on renal graft function, blood pressure and serum lipids in kidney transplant recipients: a single centre study | Zendy

Pieter Evenepoel | Zendy; Kathleen Claes | Zendy; Dirk Kuypers | Zendy; Bart Maes | Zendy; Yves Vanrenterghem | Zendy

Open Access

Impact of parathyroidectomy on renal graft function, blood pressure and serum lipids in kidney transplant recipients: a single centre study

Author(s) -

Pieter Evenepoel,

Kathleen Claes,

Dirk Kuypers,

Bart Maes,

Yves Vanrenterghem

Publication year - 2005

Publication title -

nephrology dialysis transplantation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.654

H-Index - 168

eISSN - 1460-2385

pISSN - 0931-0509

DOI - 10.1093/ndt/gfh892

Subject(s) - medicine , transplantation , parathyroidectomy , urology , renal function , endocrinology , parathyroid hormone , blood pressure , secondary hyperparathyroidism , creatinine , hyperparathyroidism , kidney transplantation , kidney , kidney disease , gastroenterology , surgery , calcium

Successful kidney transplantation is believed to reverse secondary hyperparathyroidism, but persistent disease has emerged in a significant number of allograft recipients. Parathyroid hormone (PTH) is not only involved in the aetiology of calcium/phosphate abnormalities and osteitis fibrosa, but it is also a permissive factor in the occurrence of hypertension, cardiovascular damage and dyslipidaemia. In experimental renal failure, abrogation of hyperparathyroidism by administration of a calcimimetic or parathyroidectomy (PTX) attenuates progression of renal failure. To evaluate the impact of PTX on blood pressure (BP), renal graft function and serum lipids, we performed a retrospective case-controlled study in renal graft recipients.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research