Measured creatinine clearance from timed urine collections substantially overestimates glomerular filtration rate in patients with liver cirrhosis: a systematic review and individual patient meta-analysis | Zendy

Normand L. Proulx | Zendy; Ayub Akbari | Zendy; Amit X. Garg | Zendy; Alaa Rostom | Zendy; Jim Jaffey | Zendy; Heather D. Clark | Zendy

Open Access

Measured creatinine clearance from timed urine collections substantially overestimates glomerular filtration rate in patients with liver cirrhosis: a systematic review and individual patient meta-analysis

Author(s) -

Normand L. Proulx,

Ayub Akbari,

Amit X. Garg,

Alaa Rostom,

Jim Jaffey,

Heather D. Clark

Publication year - 2005

Publication title -

nephrology dialysis transplantation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.654

H-Index - 168

eISSN - 1460-2385

pISSN - 0931-0509

DOI - 10.1093/ndt/gfh839

Subject(s) - medicine , renal function , cirrhosis , urology , liver transplantation , creatinine , kidney disease , urine , dosing , transplantation , kidney

Accurate glomerular filtration rate (GFR) assessment in patients with liver cirrhosis is important for prognostication, chronic kidney disease staging, drug dosing and identifying combined liver-kidney transplantation candidates. The objective of this study was to review the accuracy of measured creatinine clearance (MCrCl) from timed urine collections for estimating true GFR.

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