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Influence of standard haemodialysis treatment on transcription of human serum- and glucocorticoid-inducible kinase SGK1 and taurine transporter TAUT in blood leukocytes
Author(s) -
Björn Friedrich,
Dorothea Alexander,
Wilhelm K. Aicher,
Michael Duszenko,
Thomas P. Schaub,
Jutta PasslickDeetjen,
Siegfried Waldegger,
Sabine Wolf,
Teut Risler,
Florian Läng
Publication year - 2005
Publication title -
nephrology dialysis transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.654
H-Index - 168
eISSN - 1460-2385
pISSN - 0931-0509
DOI - 10.1093/ndt/gfh697
Subject(s) - sgk1 , taurine , medicine , endocrinology , osmotic concentration , glucocorticoid , epithelial sodium channel , sodium , biology , chemistry , biochemistry , organic chemistry , amino acid
Standard haemodialysis (HD) rapidly alters osmolality and composition of extracellular fluid and, thus, challenges cell volume constancy. Cell volume-sensitive genes upregulated by osmotic cell shrinkage include those encoding for taurine transporter TAUT as well as for serum- and glucocorticoid-inducible kinase SGK1.

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