Open AccessClinical outcomes and C2 cyclosporin monitoring in maintenance renal transplant recipients: 1 year follow-up study
Author(s) -
R. Marcén,
J.J. Villafruela,
J Pascual,
J.L. Teruel,
Javier Ocaña,
M. T. Tenorio,
Francisco Burgos,
J. Ortuño
Publication year - 2005
Publication title -
nephrology dialysis transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.654
H-Index - 168
eISSN - 1460-2385
pISSN - 0931-0509
DOI - 10.1093/ndt/gfh664
Subject(s) - medicine , creatinine , dosing , incidence (geometry) , therapeutic drug monitoring , transplantation , renal function , gastroenterology , urology , diabetes mellitus , surgery , pharmacokinetics , endocrinology , optics , physics
Cyclosporin A (CsA) concentration monitoring with 2 h post-dosing levels (C2) correlates with the incidence of rejection and graft outcome in de novo renal transplant patients. The advantages of this policy beyond the first 12 months remain a matter of debate. The purpose of the present work was to evaluate the C2 target ranges on CsA monitoring after the first year in stable kidney transplant patients.
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