Urinary monocyte chemoattractant protein-1 (MCP-1) is a marker of active renal vasculitis | Zendy

Frederick W.K. Tam | Zendy; JanStephan Sanders | Zendy; Abraham George | Zendy; Tarig Hammad | Zendy; Caroline Miller | Zendy; Tammy Dougan | Zendy; H. Terence Cook | Zendy; Cornelis Kallenberg | Zendy; Gill Gaskin | Zendy; Jeremy Levy | Zendy; Charles D. Pusey | Zendy

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Urinary monocyte chemoattractant protein-1 (MCP-1) is a marker of active renal vasculitis

Author(s) -

Frederick W.K. Tam,

JanStephan Sanders,

Abraham George,

Tarig Hammad,

Caroline Miller,

Tammy Dougan,

H. Terence Cook,

Cornelis Kallenberg,

Gill Gaskin,

Jeremy Levy,

Charles D. Pusey

Publication year - 2004

Publication title -

nephrology dialysis transplantation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.654

H-Index - 168

eISSN - 1460-2385

pISSN - 0931-0509

DOI - 10.1093/ndt/gfh487

Subject(s) - medicine , monocyte , chemokine , vasculitis , immunology , glomerulonephritis , chemotaxis , pathogenesis , urinary system , ccl2 , infiltration (hvac) , cytokine , systemic vasculitis , pathology , kidney , inflammation , disease , receptor , physics , thermodynamics

Macrophage infiltration and cytokine production are important in the pathogenesis of crescentic glomerulonephritis in anti-neutrophil cytoplasm antibody (ANCA)-associated vasculitis. The aim of this study was to investigate whether urinary levels of chemokines, monocyte chemoattractant protein-1 (MCP-1) and fractalkine, were useful tools for non-invasive assessment of renal vasculitis.

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