Open AccessAmelioration of myoglobinuric renal damage in rats by chronic exposure to flavonol-rich red wine
Author(s) -
Ramón Rodrigo,
Cleofina Bosco,
Patricia Herrera,
Gaston K. Rivera
Publication year - 2004
Publication title -
nephrology dialysis transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.654
H-Index - 168
eISSN - 1460-2385
pISSN - 0931-0509
DOI - 10.1093/ndt/gfh369
Subject(s) - endocrinology , medicine , glutathione peroxidase , lipid peroxidation , antioxidant , kidney , renal function , malondialdehyde , oxidative stress , wine , superoxide dismutase , chemistry , biochemistry , food science
Myoglobinuric acute renal failure causes increased oxidative stress. Since ethanol upregulates renal antioxidant enzymes and wine polyphenols behave as antioxidants, we tested the hypothesis that red wine components would ameliorate the renal damage caused by rhabdomyolysis.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom