Biocompatibility pattern of a bicarbonate/lactate-buffered peritoneal dialysis fluid in APD: a prospective, randomized study | Zendy

Andreas Fusshoeller | Zendy; M. Plail | Zendy; B. Grabensee | Zendy; J. Plüm | Zendy

Open Access

Biocompatibility pattern of a bicarbonate/lactate-buffered peritoneal dialysis fluid in APD: a prospective, randomized study

Author(s) -

Andreas Fusshoeller,

M. Plail,

B. Grabensee,

J. Plüm

Publication year - 2004

Publication title -

nephrology dialysis transplantation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.654

H-Index - 168

eISSN - 1460-2385

pISSN - 0931-0509

DOI - 10.1093/ndt/gfh326

Subject(s) - medicine , peritoneal dialysis , biocompatibility , bicarbonate , urology , continuous ambulatory peritoneal dialysis , prospective cohort study , dialysis , surgery , materials science , metallurgy

In chronic ambulatory peritoneal dialysis, bicarbonate-buffered fluids, with their neutral pH and less advanced glycosylation end-products (AGE) and glucose degradation products (GDP), have better biocompatibility than conventional peritoneal dialysis (PD) solutions. That difference may be more beneficial in automated peritoneal dialysis (APD), due to its more frequent exchanges and longer contact times with fresh dialysate. We performed a prospective, randomized study in APD patients to compare the biocompatibility of conventional and bicarbonate/lactate-buffered PD fluids.

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