Accumulation of cyanide and thiocyanate in haemodialysis patients | Zendy

Yukiko Hasuike | Zendy; Takeshi Nakanishi | Zendy; Ririko Moriguchi | Zendy; Yoichiro Otaki | Zendy; M. Nanami | Zendy; Yukie Hama | Zendy; M Naka | Zendy; Koji Miyagawa | Zendy; Masanori Izumi | Zendy; Yoshihiro Takamitsu | Zendy

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Accumulation of cyanide and thiocyanate in haemodialysis patients

Author(s) -

Yukiko Hasuike,

Takeshi Nakanishi,

Ririko Moriguchi,

Yoichiro Otaki,

M. Nanami,

Yukie Hama,

M Naka,

Koji Miyagawa,

Masanori Izumi,

Yoshihiro Takamitsu

Publication year - 2004

Publication title -

nephrology dialysis transplantation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.654

H-Index - 168

eISSN - 1460-2385

pISSN - 0931-0509

DOI - 10.1093/ndt/gfh076

Subject(s) - thiocyanate , cyanide , medicine , hemodialysis , dialysis , endocrinology , chemistry , biochemistry , inorganic chemistry

Cyanide is a toxic agent, and its detoxification product, thiocyanate, may be a major pathogenetic substance in uraemia. Recent studies examining the myeloperoxidase(MPO)/thiocyanate system have suggested a link between thiocyanate and atherosclerosis. However, inaccuracies in conventional assays for cyanide and thiocyanate have limited the understanding of their metabolism in haemodialysis (HD) patients.

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