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In vitro and in vivo models for peritonitis demonstrate unchanged neutrophil migration after exposure to dialysis fluids
Author(s) -
Angelique G.A. Welten,
Mohammad Zarei,
Jan Born,
Piet M. ter Wee,
Casper G. Schalkwijk,
B. A. J. Driesprong,
Erik Mul,
Peter L. Hordijk,
R.H.J. Beelen,
Liesbeth H.P. Hekking
Publication year - 2004
Publication title -
nephrology dialysis transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.654
H-Index - 168
eISSN - 1460-2385
pISSN - 0931-0509
DOI - 10.1093/ndt/gfh024
Subject(s) - in vivo , peritoneum , medicine , in vitro , peritoneal dialysis , mesothelial cell , peritonitis , immunology , chemokine , chemotaxis , inflammation , biochemistry , pathology , chemistry , biology , receptor , microbiology and biotechnology
Recurrent infections in peritoneal dialysis (PD) patients may alter the abdominal wall resulting in an impairment of its dialysis capacity. In this study we investigated both in vitro and in vivo the effects of mesothelial exposure to dialysis fluids on the migration of neutrophils and their capacity to clear a bacterial infection.

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