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A 51-year-old woman with asymptomatic proteinuria and haematuria was admitted for a renal biopsy. Upon admission, her blood pressure was 118/68mmHg. Urinalysis revealed proteinuria 1þ, blood 2þ, but glucose-negative. A microscopic examination showed 0–1 white and 20–30 red blood cells per high power field. Laboratory investigations showed serum total protein 6.8 g/dl, albumin 4.3 g/dl, sodium 141mmol/l, potassium 3.8mmol/l, creatinine 0.4mg/dl, blood urea nitrogen 15.3mg/dl, creatinine clearance 114ml/min, 24 h urinary protein 0.43 g and haemoglobin 13.4 g/dl. An immunological screen and radiological studies were normal. A renomedullary interstitial cell tumour was identified in the medulla of a renal biopsy specimen (Figure 1). Glomeruli were mostly normal by light microscopy. Immunofluorescence studies were negative and electron micrography of glomeruli did not reveal dense deposits.

Incidental detection of renomedullary interstitial cell tumour in a renal biopsy specimen