High permeability haemofiltration improves peripheral blood mononuclear cell proliferation in septic patients with acute renal failure | Zendy

Stanislao Morgera | Zendy; Michael Haase | Zendy; Jens Rocktäschel | Zendy; Torsten Böhler | Zendy; C. von Heymann | Zendy; Ortrud Vargas-Hein | Zendy; Dietmar Krausch | Zendy; Heidrun Zuckermann-Becker | Zendy; J. M. Müller | Zendy; W. J. Kox | Zendy; HansHellmut Neumayer | Zendy

Open Access

High permeability haemofiltration improves peripheral blood mononuclear cell proliferation in septic patients with acute renal failure

Author(s) -

Stanislao Morgera,

Michael Haase,

Jens Rocktäschel,

Torsten Böhler,

C. von Heymann,

Ortrud Vargas-Hein,

Dietmar Krausch,

Heidrun Zuckermann-Becker,

J. M. Müller,

W. J. Kox,

HansHellmut Neumayer

Publication year - 2003

Publication title -

nephrology dialysis transplantation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.654

H-Index - 168

eISSN - 1460-2385

pISSN - 0931-0509

DOI - 10.1093/ndt/gfg435

Subject(s) - peripheral blood mononuclear cell , medicine , sepsis , septic shock , renal function , mononuclear cell infiltration , hemofiltration , immunology , gastroenterology , hemodialysis , in vitro , biology , biochemistry

Continuous veno-venous haemofiltration (HF) with high permeability (HP) haemofilters is a novel approach in the adjuvant therapy of septic patients. HP haemofilters are characterized by an increased pore size which facilitates the filtration of inflammatory mediators. The present study examines whether HP-HF has an impact on peripheral blood mononuclear cell (PBMC) proliferation and whether ultrafiltrate can alter PBMC function in isolates from healthy volunteers.

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