Open AccessArterial media calcification in end-stage renal disease: impact on all-cause and cardiovascular mortality
Author(s) -
Gérard M. London,
Alain P. Guérin,
Sylvain J. Marchais,
Fabien Métivier,
Bruno Pannier,
Hasan Adda
Publication year - 2003
Publication title -
nephrology, dialysis, transplantation/nephrology dialysis transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.654
H-Index - 168
eISSN - 1460-2385
pISSN - 0931-0509
DOI - 10.1093/ndt/gfg414
Subject(s) - medicine , calcification , cardiology , kidney disease , end stage renal disease , pulse wave velocity , hemodialysis , blood pressure
Cross-sectional and follow-up studies on end-stage renal disease patients showed that arterial calcifications are associated with cardiovascular (CV) morbidity and are an independent predictor of all-cause and CV mortality. However, these studies did not examine the impact on prognosis according to the type of calcification, i.e. intimal vs medial. Arterial media calcification (AMC), a non-occlusive condition, affects haemodynamics differently from arterial intima calcification (AIC), which occurs in atherosclerotic plaques. The aim of this study was to investigate the prognostic value of AMC in relationship to all-cause or CV mortality for stable haemodialysis (HD) patients.