Contribution of lactate buffer, glucose and glucose degradation products to peritoneal injury in vivo
Author(s) -
Mohammad Zarei,
Liesbeth H.P. Hekking,
Angelique G.A. Welten,
B. A. J. Driesprong,
Inge L. Schadee–Eestermans,
Dirk Faict,
A. Leyssens,
Casper G. Schalkwijk,
R.H.J. Beelen,
Pieter M. ter Wee,
Jacob van den Born
Publication year - 2003
Publication title -
nephrology dialysis transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.654
H-Index - 168
eISSN - 1460-2385
pISSN - 0931-0509
DOI - 10.1093/ndt/gfg356
Subject(s) - mesothelial cell , peritoneum , peritoneal dialysis , peritoneal fluid , medicine , peritoneal cavity , endocrinology , andrology , pathology , surgery
Long-term peritoneal dialysis (PD) is associated with the development of functional and structural alterations of the peritoneal membrane. In this study, we investigated the contribution of low pH lactate buffer, high glucose concentration and glucose degradation products to peritoneal injury in a rat peritoneal exposure model.
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