Macrophage heterogeneity in renal inflammation
Author(s) -
Lars P. Erwig
Publication year - 2003
Publication title -
nephrology dialysis transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.654
H-Index - 168
eISSN - 1460-2385
pISSN - 0931-0509
DOI - 10.1093/ndt/gfg313
Subject(s) - medicine , inflammation , macrophage , immunology , biochemistry , chemistry , in vitro
of bone marrow-derived cells to differentiate to glomerular mesangial cells. Extraglomerular origin of the mesangial cells after injury. marrow is a reservoir of repopulating mesangial cells during glomerular remodelling. A, Plati AR et al. Glomerulosclerosis is transmitted by bone marrow-derived mesangial cell progenitors. Bone marrow transplantation attenuates murine IgA nephropathy: role of a stem cell disorder. Blockade of tubular epithelial to myofibroblast transition by hepatocyte growth factor prevents renal inter-stitial fibrosis. A role for extrarenal cells in the regeneration following acute renal failure. Hodivala-Dilke K et al. Bone marrow contributes to renal parenchymal turnover and regeneration. Smad7 inhibits fibrotic effects of TGF-beta on renal tubular epithelial cells by blocking Smad2 activation.
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