Open AccessSerum troponin T measurement in patients with chronic renal impairment predicts survival and vascular disease: a 2 year prospective study
Author(s) -
Grahame N I Wood,
Brian Keevil,
Jaya Gupta,
Robert N. Foley,
Abdalla Bubtana,
Garry McDowell,
P. Ackrill
Publication year - 2003
Publication title -
nephrology dialysis transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.654
H-Index - 168
eISSN - 1460-2385
pISSN - 0931-0509
DOI - 10.1093/ndt/gfg198
Subject(s) - medicine , troponin complex , cardiology , kidney disease , troponin t , dialysis , prospective cohort study , clinical significance , end stage renal disease , hemodialysis , troponin , myocardial infarction
Cardiovascular mortality in end-stage renal failure patients is high and early risk stratification in these patients may aid clinical management improving outcomes. Cardiac troponin T (cTnT) is a component of the cardiac myocyte which is released into the circulation following myocardial necrosis. It has been shown to be of prognostic significance in patients with unstable angina. The role of cTnT in patients with renal disease remains unclear. The aim of this investigation, therefore, was to assess the prognostic significance of cTnT in chronic renal impairment patients, pre-dialysis.
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