Modulation of autoantibody production by mycophenolate mofetil: effects on the development of SLE in (NZBxNZW)F1 mice
Author(s) -
M. Ángeles Ramos,
Celestino Piñera,
Ma ÁNgeles Setien,
Luis Buelta,
Ma.A. de Cos,
Ángel Francisco,
Ramón Merino,
M. Arias
Publication year - 2003
Publication title -
nephrology dialysis transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.654
H-Index - 168
eISSN - 1460-2385
pISSN - 0931-0509
DOI - 10.1093/ndt/gfg034
Subject(s) - mycophenolate , medicine , autoantibody , autoimmunity , immunology , mycophenolic acid , systemic lupus erythematosus , lupus erythematosus , immune system , transplantation , disease , antibody
Mycophenolate mofetil (MMF) has been successfully used to improve or prevent the development of systemic lupus erythematosus (SLE) in both humans and in several lupus-prone mice. In the present study, we evaluated mechanisms through which MMF may exert its therapeutic effect on the development of systemic autoimmunity.
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