CONVINCE in the context of existing evidence on haemodiafiltration | Zendy

Robin W.M. Vernooij | Zendy; Michiel L. Bots | Zendy; Giovanni FM Strippoli | Zendy; Bernard Canaud | Zendy; Krister Cromm | Zendy; Mark Woodward | Zendy; Peter J. Blankestijn | Zendy; Andrew Davenport | Zendy; Cláudia Barth | Zendy; Jörgen Hegbrant | Zendy; Kathrin I. Fischer | Zendy; Mariëtta Török | Zendy; Matthias Rose | Zendy

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CONVINCE in the context of existing evidence on haemodiafiltration

Author(s) -

Robin W.M. Vernooij,

Michiel L. Bots,

Giovanni FM Strippoli,

Bernard Canaud,

Krister Cromm,

Mark Woodward,

Peter J. Blankestijn,

Andrew Davenport,

Cláudia Barth,

Jörgen Hegbrant,

Kathrin I. Fischer,

Mariëtta Török,

Matthias Rose

Publication year - 2022

Publication title -

nephrology dialysis transplantation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.654

H-Index - 168

eISSN - 1460-2385

pISSN - 0931-0509

DOI - 10.1093/ndt/gfac019

Subject(s) - medicine , context (archaeology) , intensive care medicine , medline , law , paleontology , biology , political science

Haemodiafiltration (HDF) provides a greater removal of larger solutes and protein-bound compounds than conventional high-flux haemodialysis (HD). There are indications that the patients receiving the highest convection volumes of HDF result in improved survival compared with HD. However, the comparative efficacy of HDF versus HD remains unproven. Here we provide a comparative account of the methodology and aims of ‘the comparison of high-dose HDF with high-flux HD’ (CONVINCE) study in the context of the totality of evidence and how this study will contribute to reaching a higher level of certainty regarding the comparative efficacy of HDF versus HD in people with end-stage kidney disease.

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