CMV infection of the renal allograft is much more common than the pathology indicates: a retrospective analysis of qualitative and quantitative buffy coat CMV-PCR, renal biopsy pathology and tissue CMV-PCR | Zendy

Helen Liapis | Zendy

Open Access

CMV infection of the renal allograft is much more common than the pathology indicates: a retrospective analysis of qualitative and quantitative buffy coat CMV-PCR, renal biopsy pathology and tissue CMV-PCR

Author(s) -

Helen Liapis

Publication year - 2003

Publication title -

nephrology dialysis transplantation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.654

H-Index - 168

eISSN - 1460-2385

pISSN - 0931-0509

DOI - 10.1093/ndt/18.2.397

Subject(s) - buffy coat , cytomegalovirus , medicine , pathology , biopsy , betaherpesvirinae , transplantation , human cytomegalovirus , real time polymerase chain reaction , polymerase chain reaction , renal biopsy , virology , herpesviridae , viral disease , virus , immunology , biology , biochemistry , gene

Quantitative blood polymerase chain reaction (PCR) for cytomegalovirus (CMV) is used to direct therapy in kidney transplant patients, but cytomegalic inclusions are rarely found in allograft renal biopsies even with an elevated serum creatinine and apparent CMV disease. The relationship between quantitative blood CMV and renal allograft pathology is unknown.

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