Dietary potassium and laxatives as regulators of colonic potassium secretion in end-stage renal disease | Zendy

Thiriloganathan Mathialahan | Zendy

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Dietary potassium and laxatives as regulators of colonic potassium secretion in end-stage renal disease

Author(s) -

Thiriloganathan Mathialahan

Publication year - 2003

Publication title -

nephrology dialysis transplantation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.654

H-Index - 168

eISSN - 1460-2385

pISSN - 0931-0509

DOI - 10.1093/ndt/18.2.341

Subject(s) - medicine , laxative , bisacodyl , continuous ambulatory peritoneal dialysis , peritoneal dialysis , dialysis , endocrinology , gastroenterology , hemodialysis , kidney disease , end stage renal disease , constipation , colonoscopy , colorectal cancer , cancer

In end-stage renal disease (ESRD), colonic potassium (K+) secretion increases as renal K+ excretion declines. The nature of this adaptive process is poorly understood, but post-prandial increases in plasma K+ concentration may be a determining factor. In addition, even though colonic K+ secretion increases in ESRD, interdialytic hyperkalaemia is a serious problem in haemodialysis patients, which might be reduced by stimulating colonic K+ secretion still further using laxatives.

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