Lack of renoprotective effect of theophylline during aortocoronary bypass surgery | Zendy

Bernhard K. Krämer | Zendy

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Lack of renoprotective effect of theophylline during aortocoronary bypass surgery

Author(s) -

Bernhard K. Krämer

Publication year - 2002

Publication title -

nephrology dialysis transplantation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.654

H-Index - 168

eISSN - 1460-2385

pISSN - 0931-0509

DOI - 10.1093/ndt/17.5.910

Subject(s) - medicine , theophylline , nephrotoxicity , acute kidney injury , perioperative , adenosine receptor antagonist , adenosine , incidence (geometry) , antagonist , adenosine receptor , anesthesia , intensive care medicine , kidney , agonist , receptor , physics , optics

The incidence of acute renal failure (ARF) after cardiac surgery remains high, despite improvements in surgical techniques and perioperative care, and is associated with an unacceptably high mortality. The adenosine receptor antagonist theophylline has been shown to confer some benefit in experimental and clinical ARF due to ischaemia, contrast media and various nephrotoxic agents.

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