The deletion polymorphism of the ACE gene is not an independent risk factor for renal scarring in children with vesico‐ureteric reflux | Zendy

Jan Dudley | Zendy; Allyson Johnston | Zendy; Anne Gardner | Zendy; Mary McGraw | Zendy

Open Access

The deletion polymorphism of the ACE gene is not an independent risk factor for renal scarring in children with vesico‐ureteric reflux

Author(s) -

Jan Dudley,

Allyson Johnston,

Anne Gardner,

Mary McGraw

Publication year - 2002

Publication title -

nephrology dialysis transplantation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.654

H-Index - 168

eISSN - 1460-2385

pISSN - 0931-0509

DOI - 10.1093/ndt/17.4.652

Subject(s) - medicine , genotype , gastroenterology , reflux , allele , proteinuria , renal function , risk factor , kidney disease , angiotensin converting enzyme , kidney , disease , gene , genetics , biology , blood pressure

The deletion (D) polymorphism of the gene encoding angiotensin-I converting enzyme has been implicated as a risk factor for progressive renal disease in several conditions. This study was designed to evaluate the association between homozygosity for the D allele and susceptibility to renal scarring in children with vesico-ureteric reflux (VUR).

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