Randomized controlled crossover study of the effect on proteinuria and blood pressure of adding an angiotensin II receptor antagonist to an angiotensin converting enzyme inhibitor in normotensive patients with chronic renal disease and proteinuria | Zendy

Priscilla KincaidSmith | Zendy; K. F. Fairley | Zendy; David Packham | Zendy

Open Access

Randomized controlled crossover study of the effect on proteinuria and blood pressure of adding an angiotensin II receptor antagonist to an angiotensin converting enzyme inhibitor in normotensive patients with chronic renal disease and proteinuria

Author(s) -

Priscilla KincaidSmith,

K. F. Fairley,

David Packham

Publication year - 2002

Publication title -

nephrology dialysis transplantation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.654

H-Index - 168

eISSN - 1460-2385

pISSN - 0931-0509

DOI - 10.1093/ndt/17.4.597

Subject(s) - medicine , candesartan , proteinuria , angiotensin ii receptor antagonist , blood pressure , kidney disease , angiotensin converting enzyme , ace inhibitor , antagonist , angiotensin ii , endocrinology , crossover study , renin–angiotensin system , angiotensin receptor , urology , kidney , receptor , placebo , pathology , alternative medicine

Proteinuria and hypertension have independent deleterious effects on the progression of chronic renal disease. The objectives of this study were to determine whether the addition of Candesartan, an angiotensin II receptor antagonist, would reduce proteinuria and blood pressure in normotensive patients with chronic renal disease already receiving an angiotensin converting enzyme inhibitor (ACEI).

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