Long‐term renal injury in ANCA‐associated vasculitis: an analysis of 31 patients with follow‐up biopsies
Author(s) -
Herbert A. Hauer,
Ingeborg M. Bajema,
E. Christiaan Hagen,
LaureHélène Noël,
Franco Ferrario,
Rüdiger Waldherr,
Hans C. van Houwelingen,
Philippe Lesavre,
Renato Alberto Sinico,
Fokko van der Woude,
Gill Gaskin,
Cornelis A. Verburgh,
Emile de Heer,
Jan A. Bruijn
Publication year - 2002
Publication title -
nephrology dialysis transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.654
H-Index - 168
eISSN - 1460-2385
pISSN - 0931-0509
DOI - 10.1093/ndt/17.4.587
Subject(s) - medicine , vasculitis , renal biopsy , biopsy , glomerulonephritis , anti neutrophil cytoplasmic antibody , pathology , focal segmental glomerulosclerosis , glomerulosclerosis , kidney disease , gastroenterology , kidney , disease , proteinuria
We reported previously that in renal disease in relation to antineutrophil cytoplasm auto-antibodies (ANCA)-associated vasculitis, renal outcome correlates better with the percentage of normal glomeruli than with separate active lesions. This may imply that glomeruli, once affected by necrotizing and crescentic lesions, are irreversibly damaged. We quantified and evaluated the course of renal lesions in the present study.
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