Expression of nephrin in acquired human glomerular disease | Zendy

Wooseong Huh | Zendy; Dae Joong Kim | Zendy; MiKyung Kim | Zendy; Yoon Goo Kim | Zendy; Hayoung Oh | Zendy; Vesa Ruotsalainen | Zendy; Karl Tryggvason | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Expression of nephrin in acquired human glomerular disease

Author(s) -

Wooseong Huh,

Dae Joong Kim,

MiKyung Kim,

Yoon Goo Kim,

Hayoung Oh,

Vesa Ruotsalainen,

Karl Tryggvason

Publication year - 2002

Publication title -

nephrology dialysis transplantation

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.654

H-Index - 168

eISSN - 1460-2385

pISSN - 0931-0509

DOI - 10.1093/ndt/17.3.478

Subject(s) - nephrin , immunoelectron microscopy , glomerular basement membrane , membranoproliferative glomerulonephritis , congenital nephrotic syndrome , podocyte , medicine , slit diaphragm , pathology , glomerulonephritis , nephrotic syndrome , renal biopsy , membranous nephropathy , minimal change disease , proteinuria , kidney , biopsy , focal segmental glomerulosclerosis , immunohistochemistry

Nephrin is a recently identified protein, which is synthesized in the podocytes and localized in the slit diaphragm area. Nephrin is a cell adhesion molecule of the immunoglobulin superfamily, and presumably is a part of the zipper-like structure of the slit membrane. As the mutation of the gene coding nephrin induces congenital nephrotic syndrome of Finnish type, which is a prototype of nephrotic syndrome, it has been suggested that nephrin also plays a role in acquired proteinuric kidney disease.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research