Acute allograft pancreatitis associated with renal allograft rejection

Acute allograft pancreatitis is common following simultaneous pancreas and kidney (SPK) transplantation with either bladder or enteric drainage w1,2x. Allograft pancreatitis may be caused by infection, bladder drainage problems, alcohol, drugs and diet w1x. Pancreatic allograft rejection, usually occurring in the context of renal allograft rejection, may cause a syndrome similar to acute allograft pancreatitis but with certain important differences w3x. This report describes the coincidence of graft pancreatitis and acute renal allograft rejection. We suggest that graft pancreatitis in this case heralded the occurrence of renal allograft rejection. Acute renal allograft rejection should therefore be considered in the differential diagnosis of acute graft pancreatitis.