Open AccessA randomized, double‐blind, placebo‐controlled trial of supplementary vitamins E, C and their combination for treatment of haemodialysis cramps
Author(s) -
Parviz Khajehdehi,
Mohammad Mojerlou,
Saeed Behzadi,
G.A Rais-Jalali
Publication year - 2001
Publication title -
nephrology dialysis transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.654
H-Index - 168
eISSN - 1460-2385
pISSN - 0931-0509
DOI - 10.1093/ndt/16.7.1448
Subject(s) - medicine , placebo , muscle cramp , vitamin , subclinical infection , ascorbic acid , levocarnitine , gastroenterology , randomized controlled trial , vitamin c , adverse effect , carnitine , chemistry , alternative medicine , food science , pathology
Muscle cramps that improve after carnitine or vitamin E therapies are common in haemodialysis (HD) patients. Because vitamin C participates in carnitine biosynthesis, and its levels are reduced in uraemia, subclinical vitamin C depletion may contribute to HD cramps. Our aim was to determine the effects of vitamins C, E and their combination on the frequency and intensity of HD cramps.
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